At least four responses (11%) were necessary to consider the regimen sufficiently active to pursue in further studies. A first stage interim analysis was planned after enrollment of MAC glucuronide α-hydroxy lactone-linked SN-38 12 patients, with early stopping to occur if no responses Mouse monoclonal to CD152(PE) were observed (resulting in a 0.54 probability of … Continue reading At least four responses (11%) were necessary to consider the regimen sufficiently active to pursue in further studies